I am a CNRS Research Scientist in the Biophysics of Complex Systems team at Institut des Sciences Analytiques, France.

My research falls under computational molecular biophysics, physical chemistry, and integrative structural biology.

I strive to understand how biomolecular function emerges from structural dynamics by describing the atomically-detailed mechanisms involved. For this, I combine molecular dynamics simulations, machine learning, and experimental biophysics.

I investigate complex molecular mechanisms in systems ranging from short peptides to large molecular motors (myosin, ATP synthase), with the occasional venture into supra-molecular chemistry. I also contributed to characterizing the conformational dynamics and immunogenic sites of the SARS-CoV-2 spike protein in the early days of the Covid-19 pandemic. More recently, I started to explore how to apply deep learning methods to the analysis of biophysical experiments.

I am always looking for motivated students to work with, so check out the open positions or contact me directly at florian.blanc_at_isa-lyon.fr.